目的:探讨国内常见市售含氟牙膏对完整釉质及脱矿釉质的作用。方法:测定市售的3种含氟牙膏的氟含量,并选取釉质完好的牛牙及人工龋脱矿的牛牙,用3种含氟牙膏和不含氟牙膏刷洗釉面后,乳酸处理1 min,用原子吸收光谱仪测定溶出的钙量。结果:含氟牙膏组和不含氟牙膏组均能使完整釉质的溶钙量明显降低,与空白对照组相比差异有显著性;含氟牙膏组和不含氟牙膏组均能使人工龋脱矿釉质的溶钙量明显下降,并且两组间有显著性差异。结论:含氟牙膏可以增强完整釉质及人工龋脱矿釉质的抗酸溶钙能力,且效果与其氟浓度相关,氟浓度为52.63 μmol/L时可显著提高牙齿抗酸力。%Objective: The purpose of the experiment is to investigate the effect of fluoride dentifrices in China on the intact and artificial caries-like bovine enamels. Methods: The artificial caries-like lesions were created by dipping the teeth into an acid buffered solution. Both the bovine intact enamels and the artificial caries-like enamels were assigned tooth brushing 20 times every half an hour with 3 kinds of fluoride dentifrices and one kind of non-fluoride dentifrices respectively. The amount of calcium dissolved by lactic acid was determined as the susceptibility of demineralization by atomic adsorption spectrometry (AAS). Results: The group treated with fluoride dentifrice showed significantly less demineralization than the non-fluoride group (P<0.02). The effect of inhibition of acid solubility in artificial caries-like enamel after tooth brushing is significantly greater than that in intact enamel. Conclusion: Fluoride dentifrices in this experiment can prevent both intact enamel and artificial caries-like enamel from acid solubility after tooth brushing, and it seems that the effect of the fluoride dentifrices on the redemineralization is greater than the reduction of enamel solubility.
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