Pathogen Discovery and Big Data Center CAS Key Laboratory of Molecular Virology and Immunology Institut Pasteur of Shanghai Chinese Academy of Sciences University of Chinese Academy of Sciences Shanghai 200031 China;
Medical Laboratory of Taizhou Fourth People’s Hospital Taizhou 225300 China;
Viral Disease and Vaccine Translational Research Unit CAS Key Laboratory of Molecular Virology and Immunology Institut Pasteur of Shanghai Chinese Academy of Sciences Shanghai 200031 China;
Enterovirus; Hand; foot and mouth disease(HFMD); Molecular epidemiology; Evolution; Genotype;