Objective:The aim of our study was to explore the correlations between C-reactive protein(CRP) levels and clinical stages of nasopharyngeal carcinoma(NPC).Methods:We analyzed 108 cases,among them,68 cases were NPC,20 cases were benign inflammatory diseases of nasopharynx,20 cases were healthy volunteers as control.CRP was determined with immunoturbidimetry(ITM).Results:The mean concentrations of CRP in NPC(19.76 mg/L) were significantly increased compared to that in the control group(6.23 mg/L),while were significantly lower than that in benign inflammatory group(45.63 mg/L);The mean concentrations of CRP in T4 group(25.58 mg/L) were higher than that in T1 group(17.35 mg/L),T2 group(18.65 mg/L) and T3 group(15.61 mg/L).The mean concentrations of CRP in N3 group(28.04 mg/L) were higher than that in N0(17.62 mg/L),N1(21.27 mg/L),N2(18.62 mg/L) respectively,the mean concentrations of CRP in IV(25.74 mg/L) were higher than that in I(14.20 mg/L),Ⅱ(16.10 mg/L),Ⅲ(23.01 mg/L),respectively.Conclusion:The serum CRP level is associated with the occurrence of NPC and benign inflammatory disease of nasopharynx.In NPC,the CRP level has positive relationship with the TNM stage.
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