Lung cancer is one of the leading causes of cancer-related deaths,and 85%of lung cancer deaths are a result of non-small cell lung cancer(NSCLC).Most patients with NSCLC are diagnosed with advanced inoperable disease making comprehensive systemic chemotherapy as the main treatment method.Angiogenesis is a crucial regulator of the growth,invasion,and metastasis of human malignancies,including lung cancer.The combined
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