目的 比较新型抗抑郁药帕罗西汀、舍曲林、艾司西酞普兰在儿童情绪障碍中的应用.方法 共纳入使用帕罗西汀、舍曲林、艾司西酞普兰的儿童情绪障碍患者60例,根据病历病情记录分别在治疗前及治疗第2、4、6周末采用临床疗效总评量表(CGI)评定临床疗效,用不良反应量表(TESS)评定不良反应.结果 帕罗西汀组有效率为83.3％,舍曲林组有效率为88.9％,艾司西酞普兰组有效率为91.7％.总有效率为86.7％.不良反应发生率帕罗西汀组为20％,舍曲林组为22.2％,艾司西酞普兰为25％.结论 新型抗抑郁药对儿童情绪障碍安全有效.%Objective To compare the clinical usage of new type antidepressant drugs - paroxetine, sertraline, escitalo-pram in emotional disorders of Childrenhood. Methods 60 cases of emotional disorders of childrenhood were treated with paroxetine , sertraline, escitalopram were included in the study. The clinical efficacy of each patient was assessed with the Clinical Global Impression ( CGI) before treatment and at treatment of 2, 4, 6 weekend. The side effects were recorded by using Treatment Emergent Symptom Scale (TESS). Results The effective rate was 83. 3% in the paroxetine group, the sertraline group was 88. 9% , escitalopram effective rate was 91. 7%. The total effective rate was 86. 7%. The side effects of paroxetine group was 20% , the side effects of sertraline group was 22. 2% , and the side effects of escitalopram was 25%. Conclusion The new type antidepres-sants drugs are safe and effective for emotional disorders of childrenhood.
展开▼
