井穴刺血对卒中后认知障碍患者认知功能恢复及预后的影响

摘要

Objective To observe the effect of bloodletting at Jing-well points on the recovery of cognitive function and prognosis in patients with post-stroke cognitive impairment. Method One hundred patients with post-stroke cognitive impairment were enrolled and divided by the random number table into two groups, with 51 cases in the observation group and 49 cases in the control group. The control group was intervened by conventional treatment, while the observation group was additionally given bloodletting at Jing-well points. The two groups were observed and compared in terms of Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), Barthel Index (BI), and the plasma cortisol level before and after treatment. The therapeutic efficacy and occurrence rate of adverse reactions of the two groups were also compared. Result After treatment, the MMSE, MoCA and BI scores all increased in the two groups, but the scores of MMSE, MoCA and BI in the observation group were higher than those in the control group (P<0.05). The total effective rate was 94.1％ in the observation group, higher than 71.4％ in the control group (P<0.05). The plasma cortisol level dropped after treatment in both groups (P<0.05), and the level in the observation group was lower than that in the control group (P<0.05). The occurrence rate of adverse reactions was 7.8％ in the observation group, lower than 22.4％ in the control group (P<0.05). Conclusion Bloodletting at Jing-well points as assistant can effectively improve the mental state, cognitive function and activities of daily living, and to some extent reduce the happening of adverse reactions in the treatment of post-stroke cognitive impairment.%目的 观察井穴刺血治疗对卒中后认知障碍患者认知功能恢复及预后的影响.方法 选取100例卒中后认知障碍患者,采用随机数字表法将患者分为两组,观察组51例,对照组49例.对照组给予常规治疗方法进行治疗,观察组在对照组基础上进行井穴刺血治疗.观察对比两组患者治疗前后简易精神状态检查量表(MMSE)、蒙特利尔认知评估量表(MoCA)、日常生活活动能力量表(BI)评分以及血浆皮质醇表达水平,比较两组患者临床疗效以及不良反应发生率.结果 治疗后,两组MMSE、MoCA、BI评分都有所提高,但观察组MMSE、MoCA、BI评分均高于对照组(P<0.05).观察组总有效率为94.1％,高于对照组的71.4％(P<0.05).治疗后,两组患者血浆皮质醇表达水平有所降低(P<0.05),观察组血浆皮质醇低于对照组(P<0.05).观察组不良反应发生率为7.8％,低于对照组的22.4％(P<0.05).结论 运用井穴刺血辅助治疗卒中后认知障碍患者,能有效改善患者的精神状态以及认知功能,提高患者的日常生活能力,能一定程度降低不良反应,效果显著.