灸结合治疗支气管哮喘临床缓解期疗效观察

摘要

Objective To investigate the clinical efficacy of gentle moxibustion plus oral Gushen Dingchuan pills in treating the clinical remission stage of bronchial asthma.Methods Ninety patients with bronchial asthma in the clinical remission stage were randomized to groups A,B and C,30 cases each.group A received moxa-stick gentle moxibustion;group B,oral administration of Gushen Dingchuan pills;group C,moxa-stick gentle moxibustion plus oral administration of Gushen Dingchuan pills.The course of treatment was three months in all the three groups.The TCM symptom score and the Asthma Control Test (ACT) score were recorded and serum immunoglobulin E (IgE) content was measured in the two groups before and after treatment.The clinical therapeutic effects were compared between the groups.Results The total efficacy rate was 76.7％ in group A,80.0％ in group B and 93.3％ in group C.there was a statistically significant difference in the total efficacy rate between group C and group A or B (P＜0.05).There were statistically significant pre-/post-treatment differences in the TCM symptom score,the ACT score and serum IgE content in all the three groups (P＜0.01).There were statistically significant post-treatment differences in the TCM symptom score,the ACT score and serum IgE content between between group C and group A or B (P＜0.01,P＜0.05).Conclusion Gentle moxibustion plus oral Gushen Dingchuan pills can improve immunologic function in patients with bronchial asthma in the clinical remission stage.%目的 观察温和灸配合口服固肾定喘丸治疗支气管哮喘临床缓解期的临床疗效及其作用机制.方法 将90例支气管哮喘临床缓解期患者随机分为A组、B组和C组,每组30例.A组采用艾条温和灸治疗,B组采用口服固肾定喘丸治疗,C组采用艾条温和灸配合口服固肾定喘丸治疗.3组疗程均为3个月.观察3组治疗前后中医症状评分、哮喘控制测试(ACT)评分及血清免疫球蛋白E(IgM)含量的变化情况,并比较各组临床疗效.结果 A组总有效率为76.7％,B组为80.0％,C组为93.3％.C组总有效率与A组和B组比较,差异均具有统计学意义(P＜0.05).3组治疗后中医症状评分、ACT评分及血清IgE含量与同组治疗前比较,差异均具有统计学意义(P＜0.01).C组治疗后中医症状评分、ACT评分及血清IgE含量与A组和B组比较,差异均具有统计学意义(P＜0.01,P＜0.05).结论 温和灸配合口服固肾定喘丸能提高支气管哮喘临床缓解期患者的免疫功能.