甲基丙烯酸酯基对胆酸甾核骨架上氢原子化学位移的影响

摘要

1HNMR can be employed to determine the molecular structures of bile acid and its derivatives. This paper studies addresses the effects of methylacrylate on chemical shift of hydrogen on bile acid steroids skeleton. Results show that chemical shift of hydrogen alters in order with methylacrylates substituting hydroxyl group hydrogen atoms of bile acid one by one.%在研究胆汁的应用过程中，应用氢核磁共振光谱。HNMR确定了合成的多种有机化合物的结构。本文研究胆汁酸分子中引入甲基丙烯酸酯基对甾体骨架上氢原子化学位移（δ）的影响。结果显示，随着甾核羟基上氢原子依次被甲基丙烯酸酯基取代，甾核骨架上特征氢原子的化学位移依次发生变化。