辨证治疗慢加急性肝衰竭临床研究

摘要

Objective :To investigate the clinical efficacy of traditional integrated western medicine in treatment of acute-on-chronic liver failure .Methods :160 cases with HBV-associatedacute-on-chronic liver failure and who were di-vided into the control group and treatment group according into the order to hospital ,the control group were given con-ventional western medicine treatment ,the treatment group were given traditional integrated western medicine treatment , the treatment total efficacy ,PTA 、HBV-DNA and complications of two groups were observed and compared .Results :The total efficacy of treatment group was better than control group after 2 months(P< 0 .05) ;the liver function recovery , PTA 、HBV-DNA improvement of treatment group was significant(P< 0 .05) ;the complications of treatment group was obvious lower(P< 0 .05) .Conclusion :Compared with conventional western medicine treatment ,the traditional integrated western medicine in treatment of acute-on-chronic liver failure was better ,and which had lower adverse reaction and com-plications .%目的：探讨中医辨证论治配合西药治疗慢加急性肝衰竭临床效果。方法：选取我院接收的160例乙型肝炎相关性慢加急性肝衰竭的患者，并将其按照入院先后分为对照组和治疗组，对照组采用常规西药治疗方案，治疗组在同等常规西药治疗规格的基础上进行中医结合治疗，分别观察记录比较两组患者治疗有效率、PTA 、HBV-DNA 以及并发症的发生率。结果：经过2个月的治疗后，与对照组相比，治疗组治疗有效率明显较好（P＜0．05）；治疗组患者的肝功能恢复程度、PTA 及 HBV-DNA 的改善较为显著（P＜0．05）；治疗组患者的并发症发生率明显较低（P＜0．05）。结论：采用中西医结合的方法治疗慢加急性肝衰竭，临床效果显著优于单纯常规西药治疗，且具有不良反应发生率低、并发症发生率低的特点。