足三里穴位注射新斯的明对脓毒症肠功能障碍的疗效观察

摘要

Objective:To discuss the clinical therapeutic effect and its mechanism of Zusanli acupoint injection of neostigmine in treatment of intestinal dysfunction in sepsis .Methods :100 patients with sepsis were randomly divided into treatment group and control group ,each of 50 cases .They were given Zusanli acupoint injection of neostigmine treat‐ment and conventional Western medical treatment .The indexes and criteria for grading of two groups were compared . Results :The patients in the treatment group in the ICU time was shorter than the control group;the case fatality rate (4% ) was lower than that of control group (16% ) ,the difference was significant statistically significant (P<0 .05) .Be‐fore and after the treatment of the indicators to improve the situation ,The treatment group was superior to the control group in the blood lactic acid level and abdominal pressure;after treatment ,SIRS score ,MODS score ,TCM syndrome score and intestinal dysfunction score were lower than those of the control group ,the difference was significant statistical‐ly significant (P<0 .05) .Conclusion:Zusanli acupoint injection of neostigmine on the treatment of intestinal dysfunction in sepsis ,efficacy significantly to multiple roles ,conducive to promoting the recovery of gastrointestinal function and prognosis .%目的：探讨足三里穴位注射新斯的明对脓毒症肠功能障碍的临床疗效及其作用机制。方法：将100例脓毒症肠功能障碍患者随机分为治疗组和对照组，各50例，分别加用足三里穴位注射新斯的明治疗和给予西医常规药物治疗，比较两组各项检测指标和评分指标。结果：治疗组患者入住IC U时间短于对照组，病死率（4．0％）低于对照组（16．0％），比较差异显著（ P＜0．05）；从治疗前后各项指标改善情况来看，治疗组在血乳酸水平、腹腔压力方面均优于对照组，治疗后SIRS评分、M ODS评分、中医证候评分和肠功能障碍评分均低于对照组，比较差异显著（P＜0．05）。结论：足三里穴位注射新斯的明治疗脓毒症肠功能障碍疗效显著，可起到多重作用，利于促进患者肠功能恢复及病情转归。