Effect of IUD with Indomethacin on Rabbits Endometrium by Enzyme Histochemistry

摘要

The present paper reported the observation of the effect of IUD with indomethacin on enzyme activities of succinic dehydrogenase ( SDH ),nonspecific esterase (NSE) and ATPase in endomtrium of rabbits, and the comparison with copper intrauterine devices, silicon rubber and IUD with copper and indomethacin. The results indicated= 1. In the group of indomethacin, the enzyme activities of SDH, NSE and ATPase were increased, while they' were obviously decreased in [UD with copper. In the group of IUD with copper and indomethacin the enzyme activities also decreased, but were higher than those observed in the silicon rubber group. 2. The damage to endometrium was obvious in IUD with copper. The damage to epithelium of endometrium in structure and function by IUD with indomethacin was found to be lower.