Hydrolysis of carboxylate ester catalyzed by a new artificial abzyme based on molecularly imprinted polymer

摘要

＜正＞ A new kind of artificial abzyme MIP-3, which contains N-phenyl benzonic amide group and "nano-channel" formed by embedded ZnO nano materials, and is imprinted by a transition-state analogue of p-nitrophenyl methyphosphonate in the hydrolysis of p-nitrophenyl acetate, was prepared by radical co-polymerization. Hydrolytic kinetics of p-nitrophenyl carboxylate catalyzed by MIP-3 was investigated. The results showed that the artificial abzyme exhibited notable substructure selectivity and strong catalytic ability in hydrolysis of p-nitrophenyl acetate.