老年2型糖尿病病人心血管疾病危险因素控制水平与年龄的关联研究

摘要

目的 了解老年2型糖尿病(T2DM)病人心血管疾病危险因素的控制情况,并探讨不同年龄组危险因素控制的差异及其与年龄的关系.方法 基于"江苏省社区糖尿病综合干预及应用研究"的基线调查数据,纳入其中年龄>60岁的T2DM对象共13135例,按年龄划分为低(60~岁)、中(70~岁)、高(≥80岁)3个年龄组.探讨年龄与血糖、血脂、血压、及体质量指数(BMI)达标的关系.结果 老年T2DM病人血压、血糖、血脂和BMI的达标率分别为47.14%、42.92%、13.52%和36.90%,仅有2.21%的病人四个指标同时达标,不同年龄组血压、血脂、BMI达标率差异有统计学意义.多因素分析显示,血压、血脂和BMI的达标率与年龄有关,年龄越大,血压达标率越低,血脂和BMI的达标率越高.结论 老年T2DM病人心血管疾病危险因素的总体控制水平较差,应加强对血脂的控制.%Objective To investigate the control rate of cardiovascular disease risk factors ( CRFs) and to explore the influence of age on the control rate in patients with T2DM. Methods A cross-sectional study was carried out on the basis of Comprehensive Research on the Prevention and Control of the Diabetes in Jiangsu. A total of 13135 patients aged over 60 years with T2DM were enrolled in this study. Patients were divided into three groups by age:younger elderly, middle elderly, and older elderly. The control of CRFs including glycosylated hemoglobin ( HbA1c) , lipid profiles, blood pressure and body mass index ( BMI) were evaluated. Multiple Logistic regression analysis was performed to assess the association between age and the control rate. Results The proportion of the elderly who achieved target control of blood pressure, HbA1c, lipid profiles and BMI was 47. 14%, 42. 92%, 13. 52% and 36. 90% respectively. The control rate of blood pressure, lipid and BMI was different in different age groups. After adjusted for sex, area, duration of diabetes, drug usage and compliance with medication, there were significant associations between age and the control rate of blood pressure, lipid and BMI. The proportion of patients achieving target control of BMI and lipid profiles showed increasing trend with the increase of age, but the proportion of patients achieving target of blood pressure showed decreasing trend. Conclusions The control rate of risk factors for CVDs is unsatisfied in elderly T2DM patients. In addition, personalized intervention measures should be taken into consideration and multiple kinds of health education should be carried out among the elderly with T2DM.