Impact of formulation parameters on physical characteristics of spray dried nanoemulsions and their reconstitutions

摘要

Nanoemulsion as small droplet dispersion allows them to uniformly deposit on substrates,increases the rate of bioavailability,absorption and has a better uptake.Although it is generally accepted that nanoemulsions are stable for years,Oswald ripening which can damage nanoemulsion has been reported[1].In this study,converting nanoemulsion as liquid formulation into solid powders was attempted by using spray drying method.The obtained powders were then characterized,reconstituted and compared to the initial nanoemulsion.