Gastric adenocarcinoma with hepatoid adenocarcinoma:A case report and literature review

摘要

Objective Hepatoid adenocarcinoma of the stomach is exceedingly rare.Only a few cases have been reported worldwide.In this report,we describe our pathological findings along with a review of the literature to improve our understanding of the disease and prevent misdiagnosis,as well as to provide evidence for its treatment and prognosis.Methods A 68-year-old male patient was admitted to our hospital(Dalian Municipal Central Hospital,Dalian,China)complaining of upper abdominal pain.Physical examination and regular laboratory blood tests showed no obvious abnormalities.A contrast-enhanced computed tomography scan displayed a 3.0 cm×3.0 cm mass in the gastric antrum,but no metastasis was found in the adjacent organs.Results A radical gastrectomy was performed and postoperative histopathology showed a moderately differentiated adenocarcinoma with partial hepatoid adenocarcinoma.Conclusion Hepatoid adenocarcinoma of the stomach is a rare malignant neoplasm.The diagnostic criteria for hepatoid adenocarcinoma of the stomach depends mainly on the clinical,radiographic,and histopathological findings.Pathomorphology and immunohistochemical staining can be utilized to confirm the diagnosis.