Cannabinoid pharmacology and its therapeutic uses in Alzheimer’s disease

摘要

Alzheimer’s disease(AD)is a chronic neurodegenerative disease,which is difficult to diagnose in its early stages.It is associated with aging and consists of a decline in cognitive functions,memory,and other mental activities.Some pathophysiological markers are associated with AD progression and worsening,such as the deposition and intracellular accumulation of senile plaques containing amyloid-β(Aβ)peptides,and tau protein hyperphosphorylation,leading to the formation of neurofibrillary tangles.