Impact of the metabolicsyndrome on the evolution of neurodegenerative diseases

摘要

Metabolic syndrome(MetS)might be defined as the simultaneous accumulation of s everal functional changes that frequently occur in adults over 60 years of age(Gomez et al.,2018).The diagnosis of MetS requires the presence of three or more factors such as high body mass,type-2 diabetes mellitus(T2DM),dyslipidemia,and arterial hypertension,which increase the risk of cardiovascular diseases as well as neurological complications,as stroke and dementia(Dyken and Lacoste,2018).Usually,these functional changes coincide and result in insensitivity for example hormones as leptin,adiponectin,and insulin(Dyken and Lacoste,2018).