Different frequencies of electroacupuncture and semen coicis decrease glial fibrillary acidic protein expression in rats with hemisection spinal cord injury

摘要

This study established the following groups of rats:a normal group,a sham surgery group,a spinal cord injury model group,a low-frequency electroacupuncture group,a high-frequency electroacupuncture group and a semen coicis group.In all but the normal and sham surgery groups,the left half of T10 was transected.Four hours after model induction,5-Hz and 100-Hz electroacupuncture were used to stimulate the acupoints Huantiao (GB 30),Zusanli (ST 36),Zhiyang (DU 9) and Xuanshu (DU 5),or crude extract from semen coicis was intraperitoneally injected,for 8 consecutive weeks.The results indicated that electroacupuncture stimulation and intraperitoneal injection of semen coicis improved the morphology of spinal cord tissue,promoted the recovery of motion-evoked potentials,suppressed glial fibrillary acidic protein expression,and ameliorated motor function in rats with hemisection spinal cord injury.The effects of high-frequency (100 Hz) electroacupuncture and semen coicis were significant.