Calcium alginate gel(CAG) has been shown to successfully model aneurysm embolization within a short period of time.However,gradually degrading CAG potentially results in aneurysm recanaliza-tion.In the present study,a regenerative embolic material was designed by seeding rat fibroblasts in a CAG.The study investigated the feasibility of constructing a 3-dimensional culture system.The fibroblasts grew well and firmly attached to the CAG.CAG was conducive for fibroblast growth,and resulted in a 3-dimensional culture system.Results show that CAG can be used theoretically as a vascular,regenerative,embolic material.
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