Stem cell therapy for retinal ganglion cell degeneration

摘要

The prospects of stem cell therapy for retinal ganglion cell(RGC)degeneration in human:RGC degeneration is a common pathologic cause of glaucoma and optic neuropathies,which are the leading cause of irreversible blindness and visual impairment in developed countries,currently affecting more than 100 million people worldwide.Intraocular pressure lowering can slow down glaucoma progression in a proportion of patients.Also,there is still no effective therapy for optic neuropathies.Besides,the degenerated RGCs in glaucoma cannot