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Curve interpolation model for visualising disjointed neural elements

机译:可视化离散神经元的曲线插值模型

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摘要

Neuron cell are built from a myriad of axon and dendrite structures. It transmits electrochemical signals between the brain and the nervous system. Three-dimensional visualization of neuron structure could help to facilitate deeper understanding of neuron and its models. An accurate neuron model could aid understanding of brain's functionalities, diagnosis and knowledge of entire nervous system. Existing neuron models have been found to be defective in the aspect of realism. Whereas in the actual biological neuron, there is continuous growth as the soma extending to the axon and the dendrite; but, the current neuron visualization models present it as disjointed segments that has greatly mediated effective realism. In this research, a new reconstruction model comprising of the Bounding Cylinder, Curve Interpolation and Gouraud Shading is proposed to visualize neuron model in order to improve realism. The reconstructed model is used to design algorithms for generating neuron branching from neuron SWC data. The Bounding Cylinder and Curve Interpolation methods are used to improve the connected segments of the neuron model using a series of cascaded cylinders along the neuron's connection path. Three control points are proposed between two adjacent neuron segments. Finally, the model is rendered with Gouraud Shading for smoothening of the model surface. This produce a near-perfection model of the natural neurons with attended realism. The model is validated by a group of bioinformatics analysts' responses to a predefined survey. The result shows about 82% acceptance and satisfaction rate.
机译:神经元细胞由无数的轴突和树突结构构成。它在大脑和神经系统之间传输电化学信号。神经元结构的三维可视化可以帮助促进对神经元及其模型的更深入了解。准确的神经元模型可以帮助理解大脑的功能,诊断和整个神经系统的知识。已经发现,现有的神经元模型在真实性方面是有缺陷的。而在实际的生物神经元中,随着躯体延伸到轴突和树突而持续生长。但是,当前的神经元可视化模型将其呈现为不连续的部分,这些部分极大地介导了有效的真实感。在这项研究中,提出了一种由边界圆柱,曲线插值和Gouraud阴影组成的新重建模型,以可视化神经元模型,从而提高真实感。重建的模型用于设计从神经元SWC数据生成神经元分支的算法。边界圆柱和曲线插值方法用于通过沿着神经元的连接路径使用一系列级联圆柱来改善神经元模型的连接段。在两个相邻的神经元段之间提出了三个控制点。最后,使用Gouraud着色渲染模型以平滑模型表面。这产生了具有参与感的自然神经元的近乎完美的模型。一组生物信息学分析人员对预定义调查的回答验证了该模型。结果表明,大约82%的接受率和满意率。

著录项

  • 来源
    《中国神经再生研究(英文版)》 |2012年第21期|1637-1644|共8页
  • 作者单位

    UTMViCubeLab, Department of Computer Graphics and Multimedia, FSKSM, University of Technology, Skudai 81310, Malaysia;

    UTMViCubeLab, Department of Computer Graphics and Multimedia, FSKSM, University of Technology, Skudai 81310, Malaysia;

    UTMViCubeLab, Department of Computer Graphics and Multimedia, FSKSM, University of Technology, Skudai 81310, Malaysia;

    College of Applied Studies and Community Service, King Saud University, Riyadh 11451, Kingdom of Saudi Arabia;

    College of Applied Studies and Community Service, King Saud University, Riyadh 11451, Kingdom of Saudi Arabia;

  • 收录信息 中国科学引文数据库(CSCD);
  • 原文格式 PDF
  • 正文语种 chi
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  • 入库时间 2022-08-19 03:44:43
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