Relevance and therapeutic potential of Cyp A targeting to block apoptosis inducing factor-mediated neuronal cell death

摘要

Programmed cell death(PCD)signaling pathways are important contributors to acute neurological insults such as hypoxic-ischemic brain damage,traumatic brain injury,stroke etc.The pathogenesis of all these diseases is closely linked with aberration of apoptotic cell death pathways.Mitochondria play a crucial role during PCD,acting as