Semaphorin 3A: from growth cone repellent to promoter of neuronal regeneration

摘要

Highlight Semaphorin 3A is a classically known axonal guidance cue that mediates axonal growth cone repulsion and collapse.Recent works,however,suggest that it may have the apparently diametrically opposite activity of promoting neuronal regeneration.During embryonic development,the axonal guidance cues facilitate the navigation of axonal growth cones towards the