APOLO IncRNA,a self-calibrating switch of root development

摘要

Long non-protein coding RNAs(IncRNAs)are emerging as impor-tant regulators of gene expression.In a series of studies,Ariel and co-workers revealed the molecular mechanisms of AUXIN REGULATED PROMOTER LOOP RNA(APOLO)IncRNA actions(Ariel et al.,2014,2020;Moison et al.,2021).APOLO integrates endogenous and exogenous signals and,in combination with an intricate network of epigenetic and transcriptional factors,controls multiple aspects of root development.Notably,APOLO acts as both positive and negative regulator to orchestrate gene expression in cis and in trans.