基于文献分析的慢性疼痛发病机制及治疗现状研究

摘要

Through consulting related literatures on modern medicine pathogenesis and treatment status of chronic pain,new clinical treatment methods were revealed and summarized.Literatures on modern medicine pathogenesis and treatment of chronic pain were retrieved from the CNKI,Wanfang Data,VIP,and Pubmed database from January 2000 to December 2016.Literatures with big influence,strong representation and new treatment method were screened.All methods were classified to summarize the pathogenesis and clinical application situation.This paper discussed the pathogenesis of peripheral sensitization,central sensitization,psychological mechanism and clinical medication.Through nearly 15 years of literature analysis,the pathogenesis of modern medicine and treatment status of chronic pain were summarized.%查阅慢性疼痛的西医发病机制及治疗现状的相关文献,发现并总结临床治疗新方法.通过检索2000年1月至2016年12月期间的CNKI、万方、维普、Pubmed数据库中慢性疼痛西医发病机制和治疗现状的文献,筛选出影响力大、代表性强、治疗方法新颖的文献,将各种方法进行分类,概括总结发病机制并分析临床应用现状.本文论述外周敏化、中枢敏化、心理机制等发病机制以及临床用药,并且通过近15年的文献分析,归纳总结了慢性疼痛的西医发病机制以及治疗现状的研究.