The changes of cycle distribution of spleen, thymus, peripheral lymphocyte and tumor cells are studied in the present study, which aims to provide basic data for object-oriented biological hadrontherapy (OOBHT). The tumor of male H22 tumor-bearing BALB/c mice was irradiated by 58 MeV/u12C6+ ions with 0, 2 or 4 Gy. After irradiation of 16 h, the cells were arrested and the cell cycle distribution was ana-
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