特异性人免疫球蛋白与传染性疾病的防治

摘要

特异性人免疫球蛋白是指针对某一特定病原体或生物毒素等的一类高免疫球蛋白制剂，是血液制品的重要品种，多用于预防和治疗一些发病率高、感染后果严重、无特效治疗方法的病原体感染，在传染性疾病的防治中具有其他药物不可比拟的优点。国外特异性人免疫球蛋白上市品种较多，而国内由于技术瓶颈约束、经济效益有限等原因，新型特异性人免疫球蛋白的研发进展缓慢。该文对多种特异性人免疫球蛋白及其对于传染病的防治作用进行了综述。%The specific human immunoglobulin is a hyperimmune globulin against a particular pathogen or biotoxin .It′s an important variety in plasma derivatives .Specific human immunoglobulin is usually used to prevent and treat pathogen in -fections with high morbidity , severe outcomes and no efficient treatment available .Thus it has unique advantages in preven-tion and management of infectious diseases .A variety of specific human immunoglobulins have been licensed abroad , but the development of new specific human immunoglobulins is slow in China due to technical constraints , limited economic benefits or for other reasons .Here we reviewed some specific human immunoglobulins and their preventive and therapeutic effect on infectious diseases .