Effects of Maca Extract on Endurance and Blood Antioxidant Enzyme Activity of Rats

摘要

[Objectives] The aim was to investigate the effects of maca extract on endurance and blood antioxidative enzyme activity of rats.[Methods]The Wistar rats treated with/without maca extract( 8. 0,16. 0,and 32. 0 g/kg) were given with free access to circulating water.The administration was conducted for 15 consecutive d. On the 16 th d,the endurance and blood malondialdehyde( MDA),superoxide dismutase( SOD) and glutathione peroxidase( GSH-Px) levels of the rats were determined. [Results] Compared with those of the rats without maca extract treatment,the swimming time before sinking of the rats administered with 8. 0,16. 0,and 32. 0 g/kg of maca extract was increased by 34. 38%,84. 25% and 126. 07%( P < 0. 01),the total swimming time was increased by 37. 42%,47. 03% and 107. 24%( P <0. 01),the times of sinking was reduced by 17. 65%,33. 28% and 55. 50%( P < 0. 05,P < 0. 01),the blood MDA level was reduced by 34.63%,54. 13% and 63. 73%( P < 0. 01),the blood SOD activity was increased by 67. 78%,108. 25% and 154. 49%( P < 0. 01),and the blood GSH-Px level was increased by 48. 57%,110. 28% and 154. 86%( P < 0. 01). [Conclusions]Macaextract has the functions of resisting fatigue and enhancing athletic,and the mechanisms are related to the reduction of blood MDA level and the increase of blood SOD and GSH-Px activity.