Objective: To analyze the diagnosis of NT-proBNP and C-reactive protein in children with Kawasaki disease, and to study its economics and significance. Methods: Twenty patients with acute Kawasaki disease and 20 patients with Kawasaki disease recovery from June 2017 to June 2018 were enrolled in our hospital. Twenty patients with respiratory infection were included in the control group. The levels of proBNP and C-reactive protein were divided into children without Kawasaki disease and coronary artery disease group, and the levels of NT-proBNP and C-reactive protein were compared. Results: The levels of NT-proBNP and C-reactive protein in the acute phase of Kawasaki disease and the recovery group of Kawasaki disease were significantly higher than those in the control group, and the acute phase group was significantly higher than the recovery group. The difference between the groups was statistically significant. In the detection of lesions in children with acute Kawasaki disease, the levels of WBC, PLT, and CRP in children with lesions were higher than those without lesions. The difference between the detection indexes and the lesions was P<0.05, but NT There was no significant difference in the level of -proBNP. There was no significant difference in NT-proBNP levels between the non-coronary lesion group and the coronary artery disease group in the acute phase of Kawasaki disease. The level of C-reactive protein in the group was significantly higher than that in the group without coronary artery disease, and the two groups were statistically significant. Conclusion: The detection of NT-proBNP and C-reactive protein in children with Kawasaki disease can accurately determine the extent of disease, and can be used as a laboratory index and treatment guidance. The combined detection accuracy of these two is more accurate, and it has important clinical significance for the diagnosis and treatment of Kawasaki disease value.
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机译：Objective: To analyze the diagnosis of NT-proBNP and C-reactive protein in children with Kawasaki disease, and to study its economics and significance. Methods: Twenty patients with acute Kawasaki disease and 20 patients with Kawasaki disease recovery from June 2017 to June 2018 were enrolled in our hospital. Twenty patients with respiratory infection were included in the control group. The levels of proBNP and C-reactive protein were divided into children without Kawasaki disease and coronary artery disease group, and the levels of NT-proBNP and C-reactive protein were compared. Results: The levels of NT-proBNP and C-reactive protein in the acute phase of Kawasaki disease and the recovery group of Kawasaki disease were significantly higher than those in the control group, and the acute phase group was significantly higher than the recovery group. The difference between the groups was statistically significant. In the detection of lesions in children with acute Kawasaki disease, the levels of WBC, PLT, and CRP in children with lesions were higher than those without lesions. The difference between the detection indexes and the lesions was P<0.05, but NT There was no significant difference in the level of -proBNP. There was no significant difference in NT-proBNP levels between the non-coronary lesion group and the coronary artery disease group in the acute phase of Kawasaki disease. The level of C-reactive protein in the group was significantly higher than that in the group without coronary artery disease, and the two groups were statistically significant. Conclusion: The detection of NT-proBNP and C-reactive protein in children with Kawasaki disease can accurately determine the extent of disease, and can be used as a laboratory index and treatment guidance. The combined detection accuracy of these two is more accurate, and it has important clinical significance for the diagnosis and treatment of Kawasaki disease value.
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