Three kinds of TNF alpha antagonists in the treatment of ankylosing spondylitis

摘要

cqvip:Objective:To study the three kinds of TNF alpha blockers treatment of ankylosing spondylitis the clinical effect, in order to select the best treatment plan, improve the level of clinical diagnosis and treatment.Method: Choose 2014-2016 in our hospital treatment of 99 cases of ankylosing spondylitis patients as the research object, the average is divided into three groups, each group of 33 cases, infliximab (Remicade, respectively adopt, in accordance with the heap, Ada wood treatment, observe the changes on the relevant index after treatment.Results: After treatment in the morning stiffness time, VAS score, BASDAI, ASDAS, blood sedimentation, c-reactive protein, MPV, propagated, PLT on indicators such as improved to some extent;On the morning stiffness time, in accordance with the heap single resistance group had the greatest reduction;ASDAS infliximab (Remicade, with single set to drop on the most obvious;VAS score and BASDAI is Ada wood sheet resistance group had the greatest reduction. On the propagated, according to the heap single resistance group had the greatest reduction;PLT, blood sedimentation, infliximab (Remicade, c-reactive protein in single resistance group had the greatest reduction;MPV is Ada wood sheet resistance group had the greatest reduction. Conclusion: The three kinds of TNF alpha antagonists' treatment of ankylosing spondylitis on clinical symptoms, signs and laboratory tests were different, each have advantages and disadvantages.