Effect of general anesthesia on hemorrheology,hemodynamics and levels of blood E,NE and COS in patients undergoing gynecological surgery

摘要

Objective: To investigate the influence of general anesthesia on hemorheology, hemodynamics and blood E, NE and COS levels in patients undergoing gynecological surgery. Methods: A total of 87 cases of gynecologic laparoscopic surgery in our hospital from November 2015 to June 2017 were selected as subjects,all patients underwent general anesthesia for surgery, at the time of T1, T2, T3,the index of EDI, ηP, whole blood viscosity of blood rheology (high, middle and low shear), hemodynamic indexes of HR, BP, E, NE, SPO2 and serum COS level were measured. Results: (1) Compared with T1, 87 patients'' HSV, MSV, LSV, ηP, EAI levels were significantly lower in T2 and T3, the difference was statistically significant, but there was no significant changes in the EDI three times;(2) Compared with T1, the levels of HR, SBP and DBP in 87 patients were significantly increased at T2 and T3, the difference was statistically significant, while the change of SPO2 levels at three moments was not statistically significant;(3) Compared with T1, the blood E, NE and COS levels in 87 patients increased significantly at T2 and T3, and the difference was statistically significant. Conclusion:Application of general anesthesia in gynecological surgery, can significantly reduce the blood viscosity of patients, but will increase the heart rate and blood pressure and blood E, NE and COS levels, therefore, during the operation, the patient''s signs should be monitored comprehensively and closely.