Cerebral angiography of collateral circulation in patients with acute cerebral infarction and its correlation with nerve injury

摘要

Objective: To assess the cerebral angiography of collateral circulation in patients with acute cerebral infarction and investigate its correlation with nerve injury. Methods: A total of 78 patients with acute cerebral infarction who were treated in the hospital between January 2015 and June 2017 were divided into collateral circulation group (n=47) and no collateral circulation group (n=31) after cerebral angiography. The differences in serum levels of nerve injury markers, neurotrophy indexes and oxidative stress indexes were compared between the two groups. Results: Serum nerve injury markers Copeptin, H-FABP, S100B and MBP levels of no collateral circulation group were significantly higher than those of collateral circulation group;serum neurotrophy indexes BDNF and NGF levels were significantly lower than those of collateral circulation group;serum oxidative stress indexes 8-OHdG and LHP levels were higher than those of collateral circulation group whereas SOD and CAT levels were lower than those of collateral circulation group. Conclusion: Cerebral angiography can accurately assess the existence of collateral circulation in patients with acute cerebral infarction, and the cerebral injury is more serious in those without collateral circulation.