缺血修饰白蛋白与急性冠状动脉综合征关系的研究进展

摘要

急性冠状动脉综合征(ACS)是常见且病死率较高的心血管急症.传统的血液中生化标志物在对ACS的早期诊断和预后评价等临床应用中存在诸多局限.作为新兴的血液中生化标志物,缺血修饰白蛋白(IMA)应用于ACS测定心肌损伤及危险分层.现对IMA的概述、形成、生物学特性及其与ACS的关系(包括诊断、治疗及预后)的最新研究进展和临床应用予以综述.%Acute coronary syndrome ( ACS ) is a common cardiovascular emergency of high mortality. In the early diagnosis and prognosis, there are many limitations of the traditional biochemical makers in clinical applications. As a new biochemical makers,ischemia modified albumin ( IMA ) used in acute coronary syndrome is playing important roles in stratification of myocardial injury and risk of ACS. Here is to review the latest general research progress of the formation, biology characters and relationship between IMA and diagnosis, treatment and prognosis of ACS.