男性乳腺癌患者的临床特征及预后分析

摘要

Objective To investigate the clinical characteristics and the prognosis of male breast cancer ( MBC ). Methods The retrospective analysis on 62 MBC cases received by Chongqing Wanzhou Fifth People's Hospital from January 2001 to February 2009 was done. The patients were divided into two groups according to the therapeutic method:observation group( n =35 )receiving comprehensive treatment with surgery as the primary,control group( n =27 )receiving only chemotherapy. After the patients were discharged,3 years follow-up was done to observe the recurrence,metastases and survival. Results During the follow-up period, QOL of the patients, local recurrence rate, remote metastases of the observation group were better than the control group;3 years survival was higher than the control group with statistically significant difference( P < 0.05 ). Conclusion MBC main clinical feature is painless breast lumps,and comprehensive treatment with surgery as the primary treatment can obtain satisfactory curative effect.%目的 探讨男性乳腺癌患者的临床特征及预后.方法 回顾性分析2001年1月至2009年2月重庆市万州区第五人民医院收治的62例男性乳腺癌患者的临床资料,并根据患者接受的治疗方法分为两组:观察组(n=35)接受以手术为主的综合治疗,对照组(n=27)接受单纯化疗.在患者治疗结束并出院后,对其进行为期3年的随访,观察患者的复发、转移及生存等情况.结果 随访期内,观察组生活质量、局部复发率、远处转移率均低于对照组,3年总生存率高于对照组,比较差异有统计学意义(P＜0.05).结论 男性乳腺癌患者的主要临床特征为无痛性乳腺肿块,采用以手术为主的综合治疗可取得较满意的治疗效果.