急性脑梗死患者血浆P选择素及D-二聚体水平与预后的关系

摘要

Objective To explore the clinical significance of relations between plasma P-selectin/D-dimer levels and prognosis in patients with acute cerebral infarction. Methods In 96 patients of acute cerebral infarction, peripheral venous blood were collected at 1 ,3 days after invasion, and neurological deficit scores were calculated by Scandinavian Stroke Scale( SSS )in 1 ,30 days after invasion. The relations between P-selectin/D-dimer average and the SSS score was statistically analyzed. Results The P-selectin/D-dimer levels of, mild, medium and serious patients were gradually increased. The average P-selectin/D-dimer levels and SSS decline was a positive linear correlation. Conclusion Plasma P-selectin/D-dimer levels after invasion can be an important index of judging condition and prognosis of patients with acute cerebral infarction.%目的 探讨急性脑梗死患者血浆P选择素及D-二聚体水平与预后关系的临床意义.方法 96例对急性脑梗死患者分别于发病后1、3 d抽取外周静脉血,测定血浆P选择素及D-二聚体水平,并于发病后1、30 d采用斯堪的纳维亚卒中量表(SSS)进行神经功能缺损评分.统计分析P选择素及D-二聚体平均水平(发病后1、3 d平均值)与SSS评分之间的关系.结果 轻、中、重型患者发病后P选择素及D-二聚体平均水平依次增高,P选择素及D-二聚体平均水平与SSS下降值呈直线正相关.结论 急性脑梗死患者发病后P选择素及D-二聚体平均水平可以作为判断病情和预后的重要指标.