高强度聚焦超声治疗胰腺癌的研究进展

摘要

High-intensity focused ultrasound( HIFU) is a non-invasive technique used for thermal abla-tion in multiple benign and malignant solid tumors. Pancreatic cancer has a dismal prognosis, and most patients are diagnosed at an inoperable stage. Chemotherapy and radiation therapy is not satisfactory enough. So,there is an urge need for new treatments to improve the situation. Clinical trials suggest that HIFU,as part of the comprehensive treatment for patients with pancreatic cancer,may increase the effective rate,median survival time,1-year survival rate and improve the quality of life.%高强度聚焦超声(HIFU)是一种无创局部热消融技术,适用于多种良恶性实体肿瘤的治疗。胰腺癌起病隐匿,恶性程度高,多数患者确诊时已失去手术机会,且化疗、放疗效果欠佳,故需要新的治疗手段改善现状。临床研究显示,HIFU作为综合治疗手段可能提高胰腺癌患者的治疗有效率、中位生存期及1年生存率,改善患者的生活质量。