亲属活体供肾移植与尸体供肾移植的临床疗效比较

摘要

目的:比较亲属活体供肾移植与尸体供肾移植的临床效果.方法:对21例亲属活体供肾移植者及22例尸体供肾移植者的资料进行分析,比较其临床疗效.结果:两组术后1年内的急性排斥反应发生率分别为14.3%和22.7%;人/肾1年、3年和5年存活率,前者分别为100%/100%、 95.2%/100%和90.5%/95.2%,后者分别为100%/100%、90.9%/95.5%和81.8%/86.4%.结论:在HLA配型和免疫抑制方案相同的情况下,亲属活体供肾移植的临床效果优于尸体供肾移植.%Objective: To compare the clinical results between living related and cadaveric donor renal transplantation.Methods: A total of 21 cases of living related donor renal transplantation and 22 cases of cadaveric donor renal transplantation were analyzed retrospectively.Results:The acute rejection rates in living donor group and cadaveric donor group were 14.3％ and 22.7％ respectively ( P ＜ 0.05 ).The 1 - ,3 - ,5 - year patient/graft survival rates were 100％/100％ ,95.2％/100％ and 90.5％/95.2％ respectively in living donor group and 100％/ 100％ ,90.9％/95.5％ and 81.8％/86.4％ respectively in cadaveric donor group.Conclusion: Living donor group has a better clinical results than that of cadaveric donor group in the same immunosuppressive regimen and HLA match.