肺结核的治疗转归与肺功能的变化关系临床研究

摘要

Objective:To observe the relationship between tuberculosis treatment outcomes and pulmonary function changes.Method:To choose 78 cases patients with secondary pulmonary tuberculosis from January 2011 to December 2012 in our hospital as the subjects.Check pulmonary function three times for all patients before treatment,treatment after 3 months and after treatment within 10 days,and analyzed the results.Result:(1)Being diagnosed secondary tuberculosis patients in with mild pulmonary function damage;(2)Secondary pulmonary tuberculosis and lesions of lung field four or more occurred restrictive ventilatory disorder;(3)After treatment with anti-tb,group B and group C tuberculosis pulmonary ventilation function and pulmonary function in patients with lesions were significantly improved than before treatment,with statistical significance(P<0.05).Conclusion:Secondary tuberculosis lung function damage is proportional to the degree of lesion invasion and were significantly improved after treatment,the damage degree of TB infestation seriously after cured still exists a certain degree of pulmonary function injury,early discovery,early treatment can improve patients’ outcomes,and pulmonary function.%　　目的：观察肺结核治疗转归与肺功能变化的关系。方法：选取2011年1月-2012年12月来本院就诊的78例肺结核患者，作为研究对象。对所有患者分别在治疗3个月、治疗5个月及治愈后10 d 内分三次对所有患者进行复查，经实验室检验和 X 线检查后排出活动期肺结核后，进行肺功能检测，并对结果进行统计分析。结果：（1）继发性肺结核患者确诊后均出现肺功能损伤；（2）继发性肺结核且病灶≥4个肺野的患者出现限制性通气障碍；（3）经抗结核治疗后，B 组和 C 组肺结核患者的肺通气功能及肺功能损伤较治疗初期均有显著的改善，比较差异有统计学意义（P<0.05）。结论：继发性肺结核肺功能损害与病灶侵袭程度成正比，治疗后其损害程度均有显著改善，肺结核侵袭程度较重者在治愈后依然存在一定程度的肺功能损伤，早发现、早治疗可改善患者的转归和肺功能。