左卡尼汀治疗小儿肺炎支原体感染合并心肌损害的疗效分析

摘要

Objective:To explore the effect of L-carnitine on children mycoplasma pneumoniae combined myocardial damage. Method:Totally 60 patients with mycoplasma pneumoniae infection from April 2010 to October 2011 were randomly divided into treatment group and control group,and 30 cases in each group. Besides the administration of azithromycin and symptomatic therapy to both the groups,the treatment group was also given L-earnitine. Then myocardial enzymes and ECG was measured and compared. Result:The myocardial enzymes of both the two groups recovered,and the treatment group seemed better(P<0.05). The ECG recovery rate of the treatment was 88.1%,and group was 66.8%. There was significant difference between the two groups(P<0.05). Conclusion:L-camitine has a protective effect on the myocardial damage caused by mycoplasma pneumoniae.%　　目的：观察与分析左卡尼汀对小儿肺炎支原体感染合并心肌损害的临床治疗效果。方法：选择2010年4月-2011年10月来本院治疗的肺炎支原体感染合并心肌损害患者60例，随机分为观察组与对照组，每组30例，对照组每天静脉注射10 mg/kg的乳糖酸阿奇霉素，1个疗程共3 d，间隔4 d后，开始实施第2个疗程，依照患儿病情治疗2~3个疗程，此外，静脉滴注能量合剂和磷酸肌酸钠进行营养心肌治疗；观察组在此基础上每天口服100 mg/kg的左卡尼汀，疗程为14 d，观察两组患儿的治疗效果。结果：两组患儿在治疗后心肌酶的各项指标均有所恢复，但观察组患儿心肌酶的各项指标降低情况明显优于对照组（P<0.05）。此外，观察组有88.1%的患儿心电图恢复正常，而对照组则只有66.8%，两组比较差异具有统计学意义（P<0.05）。结论：左卡尼汀对小儿肺炎支原体感染合并心肌损害的临床治疗安全可靠，效果良好。