目的：探讨近30年异位妊娠的变化趋势及发病相关因素的变迁特点。方法：收集1978-2007年期间发生在肇庆市端州妇幼保健院、肇庆市第一人民医院、肇庆市医学高等专科学校附属医院、肇庆市端州区人民医院的1968例异位妊娠病例，进行回顾性分析，将1968例异位妊娠患者按发生时间为顺序，每10年一个阶段划分，统计异位妊娠的发病率，统计如下发病相关因素：异位妊娠发病率、年龄、婚育史、孕产史、教育程度、既往病史：宫内节育器、生殖道感染病史、前次异位妊娠史、下腹部手术史、宫颈治疗史、吸烟史、避孕史、辅助生育技术的应用。结果：近年来，异位妊娠的发病率一直呈上升趋势。异位妊娠患者未婚、未育、孕产次数多比例明显上升。前期组异位妊娠的既往病史主要为宫内节育器史，中期组主要为生殖道感染史，而后期组异位妊娠患者的既往病史为前次异位妊娠史、下腹部手术史和生殖道感染史。后期组中宫颈治疗史，吸烟史，避孕史，辅助生育技术使用史均高于前期组和中期组。结论：近三十年异位妊娠发病相关因素发生变化，针对不同的发病相关因素采取切实可行的干预措施，更好地预防异位妊娠的发生，从而降低发病率。%Objective:To study the characters and the trend of correlation factors’ changes of ectopic pregnancy onset in 30 years.Method:1968 cases are collected from Duanzhou Maternal and Child Health Hospital,Zhaoqing No.1 Hospital,Zhaoqing Medical College Hospital and Zhaoqing Duanzhou People’s Hospital,and implemented a retrospective analysis.The cases are ranked according to time sequence that are sorted by every 10 years, and the ages,ectopic pregnancy incidences,marital histories,reproductive histories,education backgrounds,abdominal operation histories,cervical treatment histories,smoking histories,contraceptive histories and other affects are observed.Result:The incidence of ectopic pregnancy has rose in recent years,and the proportion of ectopic pregnancy patients and the unmarried motherhood is growing.The incentives of different groups are varied:IUD history in the early group,reproductive tract infections in the medium group,and the previous ectopic pregnancy histories,lower abdomen operation histories and reproductive tract infection histories in the late group.Conclusion:The result of the research is found that the preventions can be implemented according to different factors that related to pathogenesis,thereby reducing the incidence and preventing the probability of ectopic pregnancy.
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