非高危人群HCV高发感染地区丙型肝炎防治研究

摘要

Objective:To evaluate the prevalence of HCV infection with no high risk factors from Putian and researched preventive measures.Method:We analyzed the databases of HCV infection obtained from the center of disease control of Putian during 2005 and 2014 and the 1055 clinical specimens collected from the Affiliated Hospital of Putian University during 2012 and 2015.Result:The prevalence of HCV infection of Putian was obviously increase between 2005 and 2011, and then,the trend was leveled off.The prevalence of HCV infection with females was higher than males.The age of HCV-infected patients in this study was mainly between 40-60 years old.The profession of HCV infection almost was peasant. There were significant statistical difference of age between the chronic hepatitis C,liver cirrhosis and primary hepatic carcinoma(P<0.01).Conclusion:The prevalence of HCV infection of Putian coastal regions is high which would cause enough attention from clinically and the national related department. More publicity should carry out for populace to increase the rate of the perceive and take timely treatment of the HCV infection.%目的：探讨莆田市非高危人群丙型病毒肝炎感染的有关问题及防治措施。方法：分析2005-2014年莆田市疾病控制中心丙型肝炎疫情报告病例数据及2012-2015年莆田学院附属医院住院的1055例丙肝患者的临床数据。结果：2005-2011年本地区丙型病毒性肝炎发病率呈明显上升趋势，2012年后升幅趋于平稳，女性发病率明显高于男性，感染者主要分布在40~60岁这一年龄段，患者职业主要为农民，慢性丙型肝炎、肝硬化与原发性肝癌患者年龄比较，差异有统计学意义（P<0.01）。结论：莆田市一些沿海区县存在较高的丙型肝炎病毒感染率，临床上和国家相关部门应该引起足够的重视，加大宣传力度，提高人们对丙型病毒性肝炎的认知率，实现早发现，早治疗。