Studies on antibacterial screening of corm of Amorphophallus campanulatus (Roxb.)

摘要

Objective: To study the antibacterial screening of corm of Amorphophallus campanulatus (Roxb.) (A. campanulatus). Methods: Antibacterial activities of methanolic, petroleum ether and ethyl acetate extracts of corm of A. campanulatus were studied by agar diffusion technique to determine in vitro antibacterial activities. The antibacterial activity was measured with respect to the standard antibacterial drug. In addition, minimum inhibitory concentration was also determined by using serial dilution method to determine and evaluate antibacterial potency of test corm extracts of A. campanulatus. Results: The results showed significant antibacterial activities against four pathogenic bacteria. The minimum inhibitory concentration values against test bacteria were found to be remarkable range in bacteria like methicillin-resistant Staphylococcus aureus at concentration 0.25 mg/well, in Pseudomonas aeruginosa at 0.5 mg/well concentration, in Vibrio cholerae was 2 mg/well, Streptococcus pyogenes at concentration of 0.5 mg/well and Proteus mirabilis was at concentration of 2 mg/well. Conclusions: The methanolic and petroleum ether extracts are capable to maximum inhibition of the tested pathogenic bacteria.