Global pattern and trend of liver cancer survival: a systematic review of population-based studies

摘要

Aim:To describe the global pattern and trend of liver cancer survival,using data from the population-based studies or cancer registration.Methods:By searching CNKI,Wanfang Data,PubMed,Web of Science,EMBASE and SEER.All population-based survival studies of liver cancer from 1 January 2000 to 30 April 2020 were collected and evaluated by patient gender,time period,and country.The overall or age-standardized five-year relative survival rate was used to describe the pattern and changes in liver cancer survival over the past decades.Results:Globally,the highest age-standardized five-year relative survival rate was observed in Italy(18.0%,2005-2007)and the highest overall five-year relative survival rate was observed in Korea(34.6%,2012-2016),when compared to other countries.The most remarkable increase in overall five-year relative survival rate can be seen in Korea(from 10.7%during 1993-1995 to 34.6%during 2012-2016).In general,worldwide,the five-year relative survival rate of younger patients with liver cancer was higher than old people.For most countries,the five-year relative survival rate of liver cancer was slightly higher in women than in men.In China,the overall five-year relative survival rate of liver cancer in Taiwan was higher than that in other areas,while Cixian of Hebei and Qidong of Jiangsu were lower.Conclusion:Over the past decades,the survival rates of liver cancer have gradually improved,but great variations are also observed globally.Worldwide,younger patients with liver cancer have experienced a better prognosis.Gender disparity in liver cancer survival was not obvious.