Objective To evaluate the value of Osteoporosis Self-assessment Tool for Asians(OSTA)on post-menopausal osteoporosis in women with type 2 diabetes .Methods A total of 160 postmenopausal women with type 2 diabetes were detected the bone mineral density (BMD)of lumbar L1-4 ,hip femoral neck ,femoral greater trochanter , shaft of femar and Ward′s triangle according to the criteria for diagnosis of osteoporosis recommended by the world health organization .The 160 women were divided into normal bone group ,bone content reduced group and osteoporo-sis group .Risk factors such as age ,postmenopausal time ,course of type 2 diabetes were compared .The BMD of dif-ferent parts of patients′ bodies and the content of bone mineral salt were compared among the three groups .Correla-tion between the BMD and OSTA were analyzed ,and the value of OSTA for predicting the BMD was analyzed by re-ceiver operating characteristic curve(ROC)and regression analysis .Results There were significant differences on the age ,course of disease ,the BMD of different parts of patients′ bodies and the content of bone mineral salt among the three groups(P < 0 .05) .A positive correlation between the BMD and OSTA existed .Conclusion It needs further study that whether OSTA could be used asa predictor of osteoporosis .%目的：评价亚洲人骨质疏松自我筛查工具（OSTA ）指数能否作为骨折风险的初筛指标。方法 Lu-nari 双能 X 线吸收仪测量患者腰椎 L1-4，髋部股骨颈、股骨干、大转子、Ward′s 三角区的骨密度（BMD）值，并按照世界卫生组织推荐的骨质疏松诊断标准将160例患者分为骨质正常组、骨含量减少组与骨质疏松组。比较3组患者的年龄、绝经年限、糖尿病病程等危险因素的差异，及3组患者各部位的 BMD 值及矿盐水平的差异，对3组患者各部位的 BMD 值与 OSTA 指数进行相关性分析，采用受试者工作曲线（ROC）分析 OSTA 指数预测 BMD 值的价值。结果绝经后2型糖尿病（T2DM ）患者骨质疏松组、骨含量减少组、骨含量正常组，在年龄、病程两两间比较差异有统计学意义（P＜0．05）；3组患者在腰椎、股骨颈、Ward′s 区、大转子、股骨干的 BMD 值及矿盐水平，两两比较差异均有统计学意义（P＜0．05）；3组间腰椎、股骨颈、股骨干、Ward′s 三角区的 BMD 值与 OSTA 指数呈正相关关系（P＜0．05）。结论 OSTA 指数作为绝经后 T2DM 患者骨质疏松疾病筛查工具尚需进一步研究。
展开▼
