目的：探讨泪小点栓塞术联合中药的疗效。方法将不能被吸收的泪道栓塞通过下泪点植入28例中度干眼症患者的双眼内，3周后，测评患者干眼症状和体征、角膜荧光素染色情况、泪膜破裂时间（T FBU T ）和手术安全性，并通过泪液分泌实验（Schirmer Ⅰ test ，无局部麻醉）测基础泪液分泌量。随后再对随机选出的11例女性患者予以3周中药治疗。比较两组患者疗效。结果3周后，封泪管术后患者刺痛感的评分低于术前，差异有统计学意义（P＜0．05）；除下部区域外，其他各区域的角膜荧光素染色得分低于术前，差异有统计学意义（ P＜0．05）；接受中药联合治疗3周后的11例患者眼睛刺痛感、敏光性、角膜染色以及T FBU T得分低于未接受中药治疗的患者，Schirmer Ⅰ test得分高于未接受中药治疗的患者，差异均有统计学意义（ P＜0．05）。结论泪小点栓塞术联合中药治疗可以有效缓解中度干眼症患者症状和体征。%Objective To explore curative effect of lacrimal punctum embolization combined with traditional chinese medicine in patients with moderate dry eye .Methods The nonabsorbable punctal plugs were inserted in the lower punctum of both eyes in 28 patients (female 22 ,male 6) with moderate dry eye .After 3 weeks ,patients′dry eye symptoms ans signs ,conditions on cornea fluo‐rescein staining ,tear film break up time (TFBUT) and operation safety were evaluated ,and at the same time ,by the Schirmer Ⅰtest (without topical anesthesia) ,basal tear secretion were detected .Then 11 female patients randomly selected received treatment of chinese medicine for another 3 weeks .The effect were compared between the two groups .Results The score of irritation symp‐toms of the patients received punctal occlusion after 3 weeks was significantly higher than before(P<0 .05) ,and the postoperative score of cornea fluorescein staining in all zones except the inferior zone were significantly lower than the preoperative score (P<0 .05) .The score of irritation symptoms ,light sensitivity ,cornea fluorescein staining and TFBUT of 11 patients who received punc‐tal occlusion combined with the treatment of chinese medicine were significantly than that of patients who only received punctal oc‐clusion ,and the score of Schirmer Ⅰ test was significantly higher than that of patients who only received punctal occlusion (P<0 .05) .Conclusion Punctal plug occlusion combined treatment of chinese medicine can effectively relieve the signs and symptoms of patients with moderate dry eye .
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