直肠异常隐窝病灶对糖尿病患者结直肠癌的预警作用研究∗

摘要

目的：探讨直肠异常隐窝病灶(ACF)对糖尿病患者结直肠癌的预警作用。方法回顾性分析486例接受全结肠镜检查和直肠染色放大检查的糖尿病患者的临床资料，分析 ACF 对结直肠病变发生率的影响。结果ACF组患者增生性息肉、非进展型腺瘤性息肉、进展型腺瘤性息肉和结直肠癌发生率均明显高于无 ACF 组，差异有统计学意义(P <0.05)。结论ACF 增加了结直肠癌的发生率，对该类患者应提高警惕，避免漏诊。%Objective To explore the prewarning effect of rectal aberrant crypt foci(ACF)for colorectal canc-er.Methods 486 cases of diabetes were tested by the total colonoscopy and the rectum dyeing amplification.The in-fluence of ACF on the occurrence rate of colorectal lesions was analyzed.Results The occurrence rates of hyperplas-tic polyp,non-progress adenomatous polyps,progressive adenomatous polyps and colorectal carcinoma in the ACF group were significantly higher than those in the non-ACF group,the difference was statistically significant (P <0.05).Conclusion ACF increases the occurrence rate of colorectal carcinoma.These patients should be vigilant for a-voiding missed diagnosis.