308 nm准分子光治疗儿童及青少年斑秃疗效观察

摘要

Objective: To investigate the clinical efifcacy and safety of 308 nm monochromatic excimer light for the treatment of alopecia areata in children and teenagers.Methods: A total of 26 children and teenagers (age≤19 years) with 49 recalcitrant patches alopecia areata were enrolled in a self-control clinical trail. Lesion was treated twice a week by the 308 nm monochromatic excimer light for 15 treatments. Every patient selected one untreated alopecia areata patch that was used as a control site.Results: While no improvement of all the untreated alopecia areata patches were observed, the clinical efifcacy of treated patients was as follow: effective group 30 cases, and total effective rate of improvement was 61.22%.Conclusion: The 308 nm monochromatic excimer light is safe and effective for treatment of alopecia areata in children and teenagers.%目的：探讨308 nm准分子光治疗儿童及青少年斑秃的疗效及安全性。方法：用308 nm准分子光治疗26例儿童及青少年（年龄≤19岁）顽固性局灶性斑秃患者的49处皮损，每位患者留一处未照射皮损作为对照，每周治疗2次，共15次。结果：治疗有效组为30处皮损，总有效率为61.22%。未照光部位均未见毛发生长。随着治疗次数的增加，总有效率有上升趋势。结论：308 nm准分子光治疗儿童及青少年斑秃疗效高，不良反应少。