婴儿麻疹疫苗初免后发热出疹性疾病调查

摘要

目的：探讨婴儿初次注射麻疹疫苗后出现发热出疹性疾病的原因和特点．方法：对我院接受治疗的120例因麻疹疫苗初次免疫接种后出现发热出疹性疾病的患儿进行回顾性调查分析和血清抗体 ELISA，以分析其发病的特点．结果：所有调查组患儿均有不同程度的发热和出疹情况，其中86．67％的患儿体温高于38．4℃，出疹时间为（5．47±3．21） d，与对照组相比其差异显著，具有统计学意义（P ＜0．05）．麻疹免疫抗体检测结果阳性率为40．83％．结论：婴儿麻疹疫苗初免后发热出疹性疾病出现在8～9月龄的婴儿，其以体温升高，出现红色斑丘疹为主要临床症状．%AIM:To investigate causes and characteristics of rash and fever illness of infant after the initial injecting measles vaccine.METHODS:Analyze the data of 120 cases infant of rash and fever illness after primary immunization against measles vaccine in our hospital,and retrospectively examed serum anti-body ELISA,in order to analyze the characteristics of its inci-dence.RESULTS:Conditions of all children with fever and rash cases varied,and in which 86.67% of children's body tempera-ture is higher than 38.4℃,and eruption time was (5.47 ±3.21) d,which was statistically significant compared with the control group (P <0.05).And the positive rate of measles immunization antibody was 40.83%.CONCLUSION:The rash and fever ill-ness after primary immunization with measles vaccine occurs in in-fant of 8 to 9 months of age,and the main clinical symptoms were increased body temperature and erythematous papules appeared.