肺部亚厘米磨玻璃结节的螺旋CT与病理对照分析

摘要

Objective To compare the spiral CT and pathological findings of sub-centimetre pulmonary ground glass nodules(GGNs), and to improve the aaccuracy in early diagnosis.Methods The CT findings and pathologic features of 30 patients with sub-centimetre pulmo-nary GGNs in our hospital from May 2013 to June 2016 were reviewed retrospectively.The patients were divided into 3 groups according to their pathological classification,namely the benign group,the preinvasive group and the invasive group.The shape,size,margin,vacuole sign, pleural indentation,the relations with bronchi and blood vessels of the pulmonary GGNs were analyzed.Results There was no significant difference in shape,maximum diameter and margin between the benign group and the other two groups(P>0.05).Adjacent vessels changes of the lesion showed significant differences between benign group and preinvasive or invasive groups(P<0.05).And there were significant differences in size,pleural indentation,vacuole sign and adjacent vessels changes between the preinvasive group and the invasive group(P<0.05).Conclusion The comprehensive analysis of lesions size,vacuole sign,pleural indentation and adjacent vessels changes can be helpful to improve the aaccuracy of differential diagnosis on sub-centimetre pulmonary ground glass nodules.%目的 分析肺部亚厘米磨玻璃结节(GGN)的CT特征与病理结果,以期提高对此病变的早期鉴别诊断水平.方法回顾性分析我院2013年5月至2016年6月收治的30例肺内亚厘米磨玻璃结节的CT和病理资料.根据肺部病变性质分为良性组、浸润前组和浸润组(包括微浸润和浸润性腺癌),观察病变CT图像上的形态、大小、边缘、空泡征、胸膜凹陷征,有无血管穿行及异常增粗,有无邻近支气管的改变.结果 病灶大小、形态、边界情况在良性组与非良性组病变间,差异无统计学意义(P>0.05);病灶邻近血管的改变在良性组与非良性组病变间的差异有统计学意义(P<0.05);病灶大小、与胸膜的关系、空泡征、邻近血管的改变在浸润前组与浸润组病变间的差异有统计学意义(P<0.05).结论 结合病理分析肺部亚厘米GGN的大小、空泡征、与胸膜关系以及邻近血管改变等病理特征有助于提高对肺部亚厘米GGN病变的鉴别诊断准确率.