采用氮、磷、钾3因素2次D-饱和最优设计（310），通过大田试验建立了氮、磷、钾施肥量与桔梗产量和总皂苷含量的效应函数。结果表明，氮、磷、钾肥对桔梗产量的影响大小依次为氮肥〉钾肥〉磷肥；氮、磷、钾肥对桔梗总皂苷含量的影响大小依次为氮肥〉磷肥〉钾肥。对各效应函数进行频率分析法寻优结果表明，桔梗目标产量在4200--4800kg／hm2，95％置信区间的优化施肥量为N83．72～119．41kg／hm2、P2O5 64．10～134．39kg/hm2、K2O 78．80～147．20kg／hm2；桔梗总皂苷含量在5．5％以上，95％置信区间的优化施肥量为N113．37～140．12kg／hm2、P20585．96～153．44kg／hm2、K2076．86～136．38kg／hm2；桔梗高产优质高效栽培最优施肥量为N113．37～119．41kg／hm2、P20585．96～134．39kg／hm2、K2078．80～136．38kg／hm2，N、P205、K20的最优施用量配比为1：0．72～1．18：0．66～1．20。%The effect functions of nitrogen, phosphorus and potassium application codes on the yield and total sapo- nin of Platycoclon grandiflorum were established by conducting field experiments using three-factor D-saturation op- timal design （310）. The results show that the effects of nitrogen, phosphorus and potassium on yield and total sap- onin are nitrogen 〉 potassium 〉 phosphorus and nitrogen 〉 phosphorus 〉 potassium respectively. The results of the frequency analysis show that for the target yield between 4200 and 4800 kg/ha and confidence interval 95% , the optimal fertilizer application rates of N, P2O5 and K2O, are 83.72 -119.41, 64. 10 -134. 39 and 78.80 - 147.20 kg/ha respectively, and for the total saponin content over 5.5%, the optimal fertilizer application rates are 113.37 -140. 12, 85.96 -153.44 and 76. 86 -136. 38 kg/ha, respectively. Consequently, the optimal fertilizer application rates for both high yield and high quality of Platycodon grandiflorum are 113.37 -119.41, 85.96 - 134. 39 and 78.80-136. 38 kg/ha, respectively. The corresponding fertilizer ratio of N ： P2O5：K2O is 1：0. 72 - 1.18 ： 0. 66 -1.20.
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